Cardiovascular Disease Caused by Earthquake-Induced Stress

Diabetic Cardiovascular Disease Induced by Oxidative Stress

Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications, including coronary artery disease (CAD), cardiac hypertrophy, and heart failure (HF). HF represents one of the most common causes of death in patients with DM and results from DM-induced CAD and diabetic cardiomyopathy. Ox...

Disasters and the heart: a review of the effects of earthquake-induced stress on cardiovascular disease.

There is growing evidence that stress contributes to cardiovascular disease. Chronic stress contributes to the atherosclerotic process through increased allostatic load, which is mediated by the neuroendocrine and immune systems (sympathetic nervous system and hypothalamus-pituitary adrenal axis) and related chronic risk factors (insulin resistance syndrome, hypertension, diabetes, and hyperlip...

Identify potential drugs for cardiovascular diseases caused by stress-induced genes in vascular smooth muscle cells

BACKGROUND Abnormal proliferation of vascular smooth muscle cells (VSMC) is a major cause of cardiovascular diseases (CVDs). Many studies suggest that vascular injury triggers VSMC dedifferentiation, which results in VSMC changes from a contractile to a synthetic phenotype; however, the underlying molecular mechanisms are still unclear. METHODS In this study, we examined how VSMC responds und...

Inflammation-induced vasoconstrictor hyporeactivity is caused by oxidative stress.

OBJECTIVES We sought to determine the role of oxidative stress in the development of vascular dysfunction in inflammation. BACKGROUND Hyporeactivity to catecholamines and other vasoconstrictors is present in acute inflammation. Because oxidative stress plays a significant role in inflammation, impaired responsiveness may be overcome by anti-oxidants. METHODS In randomized, double-blind, cro...

Does earthquake-induced cardiovascular disease persist or is it suppressed after the major quake?